A Flock of Seagulls was started by Mike Score in 1980 in Liverpool. The band's name was taken from The Stranglers song "Toiler on the Sea", according to Mike Score. The inaugural line-up of the band featured Mike, who was previously a hairdresser, on keyboards and lead vocals, Ali Score on drums, and Frank Maudsley on bass. The band added Willie Woo on guitar; and then brought in Mark Edmondson to replace Ali on drums when the Score brothers had a falling-out. Not long afterwards, Edmondson departed to make way for a returning Ali; and shortly thereafter Woo departed the band and was replaced by teenager Paul Reynolds (of the band Cindysbeentrippin), who had been a close friend of Edmondson, at the behest of Maudsley; thus creating the band's classic line-up. After practising above Score's hair salon, the band started playing clubs and eventually got a recording contract.
Eventually, under the management of Tommy Crossan and Mick Rossi (Checkmount Limited), they began to release singles through Jive Records. The group released their debut single 'Talking' (produced by Nelson), on Bill Nelson's Cocteau label. They were then signed to major label Jive, distributed through CBS records, where they released their second single 'Telecommunication'. The single was also produced by Nelson and became a club hit. Their third release was the EP 'Modern Love is Automatic'. Originally released as a 4 track EP on both 7" and 12", the 12" edition was soon reissued adding 'Telecommunication'. This 5 track EP was also their first release in the U.S. In 1982, the group's fourth single 'I Ran (So Far Away)', produced by Mike Howlett, the former bass player of the band Gong, became a worldwide hit, reaching number 1 in Australia and the Top 10 in both the US and New Zealand. Their debut album and another single, 'Space Age Love Song', were both also successful. In late 1982, the band finally found major success in their home country with 'Wishing (If I Had a Photograph of You)', the first single from their next album Listen, which reached the Top 10. Later, the band was praised for having broken the ground for other musical acts during the advent of the video music area, but as it turned out, 1982 was the peak year of their commercial and critical success.
Mike Score initially reformed the band in 1988 in Philadelphia under the name A Flock of Seagulls with a line-up composed of himself along with numerous local musicians; consisting of guitarists Ed Berner and Dave Maerz, bass guitarist, Mike Radcliffe, keyboardist Mike Railton, and drummers' Kaya Pryor and Jonte Wilkins. This line-up expanded the following year to include drummer Mike Marquart; but was then reduced to a five-piece band consisting of Score, Berner, Pryor, Radcliffe, and Railton; and it was this line-up which released the single "Magic" that same year.
In 1994, the band's line-up changed again; this time to a formation consisting of Score, Berner, and new recruits A.J. Mazzetti (drums) and Dean Pichette (bass guitar).
In November 2003, the original line-up of Mike and Ali Score, Paul Reynolds and Frank Maudsley reunited for a one-off performance on the VH1 series Bands Reunited. In September 2004, they reformed again and did a brief tour in the United States. Though the tour continued to be advertised as the "original lineup", later shows no longer included the reunited band but was Mike Score's continuation of the original band; which by this point consisted of Score, Rodriguez, and new recruits Michael Brahm (drums), and Pando (bass guitar). Kevin Rankin replaced Brahm on drums in 2016.
On 4 February 2013, Score indicated via his YouTube account that he was pursuing his solo career. He released the singles "All I Wanna Do" in February 2013, and "Somebody Like You" in January 2014. On 1 March 2014, Score released a solo album, Zeebratta.